RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED AND ACTIVE-CONTROLLED STUDY TO ASSESS THE RELATIVE ABUSE POTENTIAL OF OXYCODONE HCL-NIACIN TABLETS COMPARED WITH OXYCODONE ALONE IN NONDEPENDENT, RECREATIONAL OPIOID USERS

Lynn R Webster,1 Robert L Rolleri,2,3 Glenn C Pixton,3 Kenneth W Sommerville31Lifetree Clinical Research, Salt Lake City, UT, USA; 2Salix Pharmaceuticals, Inc., Raleigh, NC, USA; 3Pfizer Inc, Cary, NC, USABackground: Abuse-deterrent formulations attempt to address public health and societal concerns regarding opioid abuse.Oxycodone HCl-niacin table

Objective: to identify the signs of neuropathic pain (NP) in patients with rheumatoid arthritis (RA) on the basis of the PainDETECT questionnaire and neurological examination.Patients and methods.A total of 208 RA patients (39 men and 169 women; mean age, 47.7 years) with chronic pain syndrome were examined.The patients underwent rheumatological an

MicroRNAs (miRNAs) are a class of small RNAs (sRNAs) that repress gene expression via high complementary binding sites in target mRNAs (messenger RNAs).Many miRNAs are ancient, and their intricate integration into gene expression programs have been fundamental for plant life, controlling developmental programs and executing responses what is quadru

Abstract Mandibular condylar cartilage (MCC) is a multi-zonal heterogeneous fibrocartilage containing different types of cells, but the factors/mechanisms governing the phenotypic transition across the zones have not been fully understood.The reliability of molecular studies heavily rely on the procurement of pure cell populations from the heteroge

Lettuce becomes the main ingredient of salad as one of the healthy foods.The lettuce cultivation in tropical areas is often performed in highland.To reduce soil erosion and pesticide contamination, the cultivation of lettuce plants in high open land needs to be reduced.The lettuce cultivation in hydroponic system at tropical lowland requires coolin